Epidemic <i>Clostridium difficile</i>- Associated Diarrhea: Role of Second- and Third-Generation Cephalosporins

Abstract

Physicians should consider carefully the appropriateness of second- and third-generation cephalosporin use and combination antimicrobial therapy, especially during nosocomial C difficile-associated diarrhea outbreaks (Infect Control Hosp Epidemiol 1994;15:88-94).