Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy

John M. Coffin · Science · 1995 · 2K citations

Life Sciences, Infectious Diseases, Molecular Genetics +17

RNA virus error catastrophe: Direct molecular test by using ribavirin

Shane Crotty, Craig E. Cameron, Raul Andino · Proceedings of the National Academy of Sciences · 2001 · 843 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +13

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

Shane Crotty, David Maag, Jamie J. Arnold et al. · Nature Medicine · 2000 · 818 citations

Life Sciences, Microbiology, Molecular Biology +12

Nucleotide sequence heterogeneity of an RNA phage population

Esteban Domingo, Donna L. Sabo, Tadatsugu Taniguchi et al. · Cell · 1978 · 564 citations

Life Sciences, Genetics, Molecular Biology +13

A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

Julie K. Pfeiffer, Karla Kirkegaard · Proceedings of the National Academy of Sciences · 2003 · 412 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17