Short-termed expression of interleukin-12 during experimental BLV infection may direct disease progression to persistent lymphocytosis

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by <i>Listeria</i> -Induced Macrophages

Chyi‐Song Hsieh, S E Macatonia, Catherine S. Tripp et al. · Science · 1993 · 3.1K citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

David Fiorentino, M W Bond, Timothy R. Mosmann · The Journal of Experimental Medicine · 1989 · 2.7K citations

Th2 Clones, Adaptive Immune System, T-regulatory Cell +20

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

Franz Koch, Ursula Stanzl, Patricia Jennewein et al. · The Journal of Experimental Medicine · 1996 · 928 citations · Full text

Il-12 Induction, Immunology, Immunologic Mechanism +16

Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells

S F Wolf, Patricia A. Temple, Michiko Kobayashi et al. · The Journal of Immunology · 1991 · 853 citations

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.

Ricardo T. Gazzinelli, Sara Hieny, Thomas A. Wynn et al. · Proceedings of the National Academy of Sciences · 1993 · 826 citations

Adaptive Immune System, Immunology, Immune Regulation +21