Concepedia

Intermittent Hypoxia and Stem Cell Implants Preserve Breathing Capacity in a Rodent Model of Amyotrophic Lateral Sclerosis

Nicole L. Nichols, Genevíève Gowing, Irawan Satriotomo, Lisa J. Nashold, Erica A. Dale, Masatoshi Suzuki, Pablo Avalos, Patrick L. Mulcrone, Jacalyn McHugh, Clive N. Svendsen,

American Journal of Respiratory and Critical Care Medicine · 2012 · 101 citations · 32 references

DOIFull text

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Abstract

AIH-induced respiratory plasticity and stem cell therapy have complementary translational potential to treat breathing deficits in patients with ALS.

References

32

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Koji Yamanaka, Seung Chun, Séverine Boillée et al. · Nature Neuroscience · 2008 · 1.1K citations · Full text

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A new method for the rapid and long term growth of human neural precursor cells

Clive N. Svendsen, Melanie G. Ter Borg, Richard Armstrong et al. · Journal of Neuroscience Methods · 1998 · 568 citations

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BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia

Tracy L. Baker‐Herman, David D. Fuller, Ryan W. Bavis et al. · Nature Neuroscience · 2003 · 476 citations

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Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease

Clive N. Svendsen, Maeve A. Caldwell, Jinkun Shen et al. · Experimental Neurology · 1997 · 444 citations

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