Pycnogenol attenuates the inflammatory and nitrosative stress on joint inflammation induced by urate crystals

Chondrocyte apoptosis induced by nitric oxide.

Francisco J. Blanco, Robert Ochs, Herbert Schwarz et al. · PubMed · 1995 · 629 citations

Life Sciences, Cell Biology, Pathology +8

Nitric-Oxide Mediates Suppression of Cartilage Proteoglycan Synthesis by Interleukin-1

H. I. Georgescu, Christopher H. Evans · Biochemical and Biophysical Research Communications · 1994 · 369 citations

Life Sciences, Immunology, Orthopedic Surgery +14

Hydroxyl and superoxide anion radical scavenging activities of natural source antioxidants using the computerized JES‐FR30 ESR spectrometer system

Yasuko Noda, Kazunori Anzai, Akitane Mori et al. · IUBMB Life · 1997 · 221 citations · Full text

Agriculture, Biochemistry, Food Science +17

Monocyte‐derived neutrophil chemotactic factor/interleukin‐8 is a potential mediator of crystal‐induced inflammation

Robert Terkeltaub, Claus Zachariae, Denise Santoro et al. · Arthritis & Rheumatism · 1991 · 213 citations

Life Sciences, Immunology, Pathology +16

Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol)

Tanja Grimm, Angelika Schäfer, Petra Högger · Free Radical Biology and Medicine · 2004 · 193 citations

Life Sciences, Pharmacology, Enzymology +12