Regional cardiac dysfunction is associated with specific alterations in inflammatory cytokines and matrix metalloproteinases after acute myocardial infarction in sheep

Processing of tumour necrosis factor-α precursor by metalloproteinases

A. J. H. Gearing, Paul Beckett, Marika Christodoulou et al. · Nature · 1994 · 1.2K citations

Inflammation, Medicine, Metalloprotein +4

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

Anique Ducharme, Stefan Frantz, Masanori Aikawa et al. · Journal of Clinical Investigation · 2000 · 805 citations · Full text

Heart Failure, Pathology, Biomedical Engineering +18

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens et al. · Nature Medicine · 1999 · 788 citations

Cardiomyopathy, Heart Failure, Cardiovascular Disease +11

Inflammation Dampened by Gelatinase A Cleavage of Monocyte Chemoattractant Protein-3

G. Angus McQuibban, Jiang-Hong Gong, Eric M. Tam et al. · Science · 2000 · 769 citations

Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing.

Uwe Schönbeck, François Mach, Peter Libby · PubMed · 1998 · 682 citations

Active Il-1 Beta, Immunology, Immune Regulation +19