Diastereoselective and Highly Enantioselective Henry Reactions using <i>C</i>₁‐Symmetrical Copper(II) Complexes

Abstract

Abstract Catalytic Henry reactions of aliphatic aldehydes and prochiral nitro compounds were investigated using copper(II) complexes of 14 C 1 ‐symmetrical ligands derived from (1 R ,2 R )(−)‐diaminocyclohexane. β‐Nitro alcohols with syn : anti ratios of up to 5.7 and excellent ee values for both diastereosimers were obtained.