Animal Models of Epidermolysis Bullosa: Update 2010

Epithelial detachment due to absence of hemidesmosomes in integrin β4 null mice

Ronald van der Neut, Paul Krimpenfort, Jero Calafat et al. · Nature Genetics · 1996 · 406 citations

Life Sciences, Cell Biology, Molecular Biology +14

Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

Kerstin Andrä, Hans Lassmann, Reginald E. Bittner et al. · Genes & Development · 1997 · 334 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Humanization of autoantigen

Wataru Nishie, Daisuke Sawamura, Maki Goto et al. · Nature Medicine · 2007 · 312 citations

Targeted Disruption of the <i>LAMA3</i> Gene in Mice Reveals Abnormalities in Survival and Late Stage Differentiation of Epithelial Cells

Maureen C. Ryan, Keesook Lee, Yuko Miyashita et al. · The Journal of Cell Biology · 1999 · 308 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy

Anja Fritsch, S. Loeckermann, Johannes S. Kern et al. · Journal of Clinical Investigation · 2008 · 218 citations · Full text

Medicine, Dermatology, Pathology +17