One-pot sequential Ti-/Cu-catalysis for tandem amidation/Ullmann-type cyclization: synthesis of model benzodiazepine(di)ones promoted by microwave irradiation

Leonardo Ciofi, Andrea Trabocchi, Claudia Lalli, Gloria Menchi, Antonio Guarna

Organic & Biomolecular Chemistry · 2012 · 14 citations · 36 references

Concepts

Abstract

The application of sequential Ti-/Cu-catalysis in the model one-pot synthesis of benzodiazepine(di)ones promoted by microwave irradiation demonstrates the expediency of dual catalysis in coupling-cyclization methods useful for diversity-oriented synthesis.

References

36