Angewandte Chemie International Edition · 2008 · 157 citations · 32 references
Cross-coupling ReactionEngineeringBiochemistryNatural SciencesDiversity-oriented SynthesisAlcohol DehydrogenaseOrganic ChemistryAsymmetric BiotransformationCatalysisChiral Biaryl AlcoholsChemistryAqueous MediaPalladium-catalyzed Suzuki Cross-couplingSynthetic ChemistryAsymmetric CatalysisPalladium‐catalyzed Cross‐couplingEnantioselective SynthesisBiomolecular Engineering
Two breeds of cat: A palladium-catalyzed Suzuki cross-coupling and an enzymatic reduction with an alcohol dehydrogenase from Rhodococcus sp. together enable the efficient and highly enantioselective synthesis of chiral biaryl alcohols in a one-pot process (see scheme).
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Recent developments in dynamic kinetic resolution
Hélène Pellissier · Tetrahedron · 2007 · 344 citations