Multidimensional Drug Profiling By Automated Microscopy

Zachary E. Perlman, Michael D. Slack, Feng Yan, +3

Science

Drug TargetEngineeringQuantitative PharmacologySpatial OmicsBioanalysis +17

Structural insights into a yeast prion illuminate nucleation and strain diversity

Rajaraman Krishnan, Susan Lindquist

Nature

BiologyStructural BioinformaticsNatural SciencesMolecular BiologyYeast +4

Quantitative measurement of nuclear translocation events using similarity analysis of multispectral cellular images obtained in flow

Thaddeus C. George, Stacey L. Fanning, Patricia Fitzgeral-Bocarsly, +9

Journal of Immunological Methods

Systems BiologyImage AnalysisNuclear Translocation EventsMedical ImagingSimilarity Analysis +10

Characterization and Quantitation of NF-κB Nuclear Translocation Induced by Interleukin-1 and Tumor Necrosis Factor-α

G J Ding, Paul Fischer, Robert C. Boltz, +5

Journal of Biological Chemistry

A Guide to Accurate Fluorescence Microscopy Colocalization Measurements

Jonathan Comeau, Santiago Costantino, Paul W. Wiseman

Biophysical Journal

Fluorescence MicroscopyEngineeringMicroscope Image ProcessingMicroscopyMicroscopy Method +6

Dynamics of NF κB and IκBα Studied with Green Fluorescent Protein (GFP) Fusion Proteins

Johannes A. Schmid, Andreas Birbach, Renate Hofer-Warbinek, +5

Journal of Biological Chemistry

Iκbα StudiedMolecular RegulationMolecular BiologyGreen Fluorescent ProteinNf κB +17

High content image cytometry in the context of subnuclear organization

Winnok H. De Vos, Leander Van Neste, Birger Victor Dieriks, +2

Cytometry Part A

EngineeringMicroscopyNuclear FingerprintingDigital PathologySubnuclear Organization +20

384-Channel parallel microfluidic cytometer for rare-cell screening

Brian McKenna, Abdulhafez Selim, F. Richard Bringhurst, +1

Lab on a Chip

Pmc SystemEngineeringBiosensing SystemsTime SynchronizationAnalytical Microsystems +10

A Cell Profiling Framework for Modeling Drug Responses from HCS Imaging

Alvin Yu Jin Ng, Jagath C. Rajapakse, Roy E. Welsch, +3

SLAS DISCOVERY

Drug TargetEngineeringDrug ProfilesCell Profiling FrameworkComputational Medicine +16