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A Case-Controlled Comparison of Thrombolysis Outcomes Between Wake-Up and Known Time of Onset Ischemic Stroke Patients

Dulka Manawadu, Shankaranand Bodla, Józef Jarosz, Jeff Keep, Lalit Kalra

Stroke · 2013 · 46 citations · 25 references

DOIFull text

Open access

Abstract

Thrombolysis in selected patients with WUIS is feasible, and its outcomes are comparable with those thrombolysed with 0 to 4.5 hours.

References

25

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Werner Hacke, Markku Kaste, Erich Bluhmki et al. · New England Journal of Medicine · 2008 · 6.5K citations · Full text

Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

Werner Hacke, Markku Kaste, Cesare Fieschi et al. · The Lancet · 1998 · 3.6K citations

, , +15

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

Kennedy R. Lees, Erich Bluhmki, Rüdiger von Kummer et al. · The Lancet · 2010 · 2.2K citations

, , +15

Thrombolysis with alteplase 3–4·5 h after acute ischaemic stroke (SITS-ISTR): an observational study

Nils Wahlgren, Niaz Ahmed, Antoni Dávalos et al. · The Lancet · 2008 · 567 citations

, , +14

Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study

Michael D. Hill · Canadian Medical Association Journal · 2005 · 449 citations · Full text