<i>Short Communication:</i> Molecular Characterization of HIV Type 1 BF Pol Recombinants from São Paulo, Brazil

Ana Carolina Mamana Fernandes de Souza, Cristina Mendes de Oliveira, Célia Luiza de Lima Rodrigues, Synara Alexandre Araújo Silva, José Eduardo Levi

AIDS Research and Human Retroviruses · 2008 · 16 citations · 22 references

Concepts

Abstract

In the Brazilian HIV-1 epidemic, subtypes B, C, and F1 are cocirculating in the population. Sequences of the partial pol gene from 463 HIV-1-infected patients were obtained from plasma samples and viral subtype was characterized. BF recombinants were found in 8% of the samples. Fifteen different patterns were observed. A CRF28_BF and CRF29_BF structure was found in 29.7% of the samples, CRF12_BF in 13.5%, and CRF39_BF in 2.7%. Two other patterns were identified in each of three samples. These findings could indicate a new CRF description, but to determine this a full length study is required.

References

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