Concepedia

The first 2<sup>IB</sup>,3<sup>IA</sup>-heterodifunctionalized β-cyclodextrin derivatives as artificial enzymes

Sophie Letort, David Mathiron, T. Grel, Christine Albaret, S. Daulon, Florence Djedaïni‐Pilard, Géraldine Gouhier, François Estour

Chemical Communications · 2014 · 29 citations · 31 references

DOI

Concepts

Abstract

Novel 2,3-heterodisubstituted β-cyclodextrin derivatives were designed as artificial enzymes to degrade chemical warfare agents. One of them reduced the acetylcholinesterase inhibitory potential by soman faster than its monosubstituted analog.

References

31

Acceleration of phenyl ester cleavage by cycloamyloses. A model for enzymic specificity

Robert L. VanEtten, John F. Sebastian, George A. Clowes et al. · Journal of the American Chemical Society · 1967 · 472 citations

, , +9

Sarin poisoning in Tokyo subway

Toru Suzuki, Hiroyuki Morita, Kazuyuki Ono et al. · The Lancet · 1995 · 356 citations

, , +6

Miniature organic models of enzymes

Valerian T. D’Souza, Myron L. Bender · Accounts of Chemical Research · 1987 · 274 citations

, , +11

Nerve agent stereoisomers: analysis, isolation and toxicology

H. P. Benschop, Leo P.A. De Jong · Accounts of Chemical Research · 1988 · 208 citations

, , +8

Triisobutylaluminium and Diisobutylaluminium Hydride as Molecular Scalpels: The Regioselective Stripping of Perbenzylated Sugars and Cyclodextrins

Thomas Lecourt, Alexandre Hérault, Alan J. Pearce et al. · Chemistry - A European Journal · 2004 · 172 citations

, , +11