Aflatoxin B-oxide generated by chemical or enzymic oxidation of aflatoxin B1 causes guanine substitution in nucleic acids

METHODS IN CANCER RESEARCH

H. Busch · The American Journal of the Medical Sciences · 1969 · 1.2K citations

Medicine, Cancer Biology, Oncology +12

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

PD LAWLEY, P. Brookes · Biochemical Journal · 1963 · 799 citations · Full text

Pharmacy, Biochemistry, Chemistry +9

Methylation of deoxyribonucleic acid in cultured mammalian cells by <i>N</i>-methyl-<i>N</i>′-nitro-<i>N</i>-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

P.D. Lawley, Carolyn J. Thatcher · Biochemical Journal · 1970 · 495 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530.

R. Colin Garner, Elizabeth C. Miller, James A. Miller · PubMed · 1972 · 410 citations

Life Sciences, Microbiology, Toxicology +13

Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.

David H. Swenson, Jen‐Kun Lin, Elizabeth C. Miller et al. · PubMed · 1977 · 252 citations

Veterinary Medicine, Biochemistry, Toxicology +15