New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

Mike Hutton, Corinne Lendon, Patrizia Rizzu et al. · Nature · 1998 · 3.5K citations

Life Sciences, Genetics, Neurology +14

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Matt Baker, Ian R. Mackenzie, Stuart Pickering‐Brown et al. · Nature · 2006 · 2.1K citations

Life Sciences, Genetics, Neurology +12

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Marc Cruts, Ilse Gijselinck, Julie van der Zee et al. · Nature · 2006 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +11

Tau is a candidate gene for chromosome 17 frontotemporal dementia

Parvoneh Poorkaj, Thomas D. Bird, Ellen M. Wijsman et al. · Annals of Neurology · 1998 · 1.4K citations

Life Sciences, Genetics, Neurology +13

Slowly progressive aphasia without generalized dementia

Marsel Mesulam · Annals of Neurology · 1982 · 1.2K citations

Health Professions, Neurology, Neuroscience +12