Immobilized penicillin G acylase as reactor and chiral selector in liquid chromatography

Aldehyde-agarose gels as activated supports for immobilization-stabilization of enzymes

JoséM. Guisán · Enzyme and Microbial Technology · 1988 · 594 citations

Engineering, Biochemical Engineering, Biotechnology +5

Biochemistry (4th edn)

David S. Latchman · Trends in Biochemical Sciences · 1995 · 570 citations

Biological Activity, Bioorganic Chemistry, Cellular Enzymology +5

Cross-Linked Enzyme Aggregates:  A Simple and Effective Method for the Immobilization of Penicillin Acylase

Linqiu Cao, Fred van Rantwijk, Roger A. Sheldon · Organic Letters · 2000 · 465 citations

Penicillin acylase has a single-amino-acid catalytic centre

Helen J. Duggleby, Shirley P. Tolley, Christopher P. Hill et al. · Nature · 1995 · 449 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +4

Increase in conformational stability of enzymes immobilized on epoxy-activated supports by favoring additional multipoint covalent attachment☆

César Mateo, Olga Abián, Roberto Fernández‐Lafuente et al. · Enzyme and Microbial Technology · 2000 · 345 citations

Engineering, Biochemistry, Protein Folding +9