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The Chromosomes of the Field Mouse <i>Akodon azarae</i> (Cricetidae, Rodentia) with Special Reference to Sex Chromosome Anomalies
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1967
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CytogeneticsGeneticsSex Chromosome AnomaliesReproductive BiologyDosage Compensation MechanismSex DifferencesPublic HealthChromosome 22GameteRodent ModelsGenetic VariationChromosomal RearrangementSex ChromosomesPopulation GeneticsField MouseBiologyChromosome DynamicsDevelopmental BiologyEvolutionary BiologySpecial ReferenceChromosome BiologyX Chromosome InactivationMedicineChromosome 9
The chromosomes of the field mouse <i>Akodon azarae</i> have been investigated. In males the diploid chromosome number is 38, with XY sex chromosomes. The four types of chromosome constitution in females are as follows: (a) 38 chromosomes with XX sex chromosomes; (b) 38 chromosomes Xx, the x being a grossly deleted X chromosome; (c) 38/37 Xx/XO sex chromosome mosaic; and (d) 37 chromosomes with an XO sex chromosome complement. This variability in females is believed to result from a dosage compensation mechanism ranging from X chromosome inactivation to total elimination of the X chromosome.