A Placebo‐controlled Double‐blind Study of Epalrestat (ONO‐2235) in Patients with Diabetic Neuropathy

Diabetes Mellitus and Its Degenerative Complications: A Prospective Study of 4,400 Patients Observed Between 1947 and 1973

J Pirart · Diabetes Care · 1978 · 1.3K citations

Medicine, Endocrinology, Internal Medicine +10

Aldose Reductase Inhibition Improves Nerve Conduction Velocity in Diabetic Patients

Roman Judzewitsch, Jonathan B. Jaspan, Kenneth S. Polonsky et al. · New England Journal of Medicine · 1983 · 314 citations

Medicine, Pharmacology, Pharmacotherapy +17

Regeneration and Repair of Myelinated Fibers in Sural-Nerve Biopsy Specimens from Patients with Diabetic Neuropathy Treated with Sorbinil

Anders A. F. Sima, Vera Bril, Virgil Nathaniel et al. · New England Journal of Medicine · 1988 · 294 citations

Medicine, Endocrinology, Neurology +12

Nerve Glucose, Fructose, Sorbitol,<i>myo</i>-Inositol, and Fiber Degeneration and Regeneration in Diabetic Neuropathy

P. James B. Dyck, Bruce R. Zimmerman, Todd H. Vilen et al. · New England Journal of Medicine · 1988 · 248 citations

Medicine, Biochemistry, Neurology +12

TREATMENT OF SEVERELY PAINFUL DIABETIC NEUROPATHY WITH AN ALDOSE REDUCTASE INHIBITOR: RELIEF OF PAIN AND IMPROVED SOMATIC AND AUTONOMIC NERVE FUNCTION

Jonathan B. Jaspan, Kevan C. Herold, Ricardo A. Maselli et al. · The Lancet · 1983 · 143 citations

Medicine, Endocrinology, Neurology +10