GLUCOSE, INSULIN AND SOMATOSTATIN INFUSION FOR THE DETERMINATION OF INSULIN SENSITIVITY

Y. Harano, S Ohgaku, Hideki Hidaka, +4

The Journal of Clinical Endocrinology & Metabolism

ObesityMetabolic SyndromeDiabetes ManagementBorderline Glucose ToleranceMedicine +13

Effects of a new aldose reductase inhibitor on various tissues in vitro.

Hiroshi Terashima, K. Hama, Reiko Yamamoto, +4

Journal of Pharmacology and Experimental Therapeutics

Long‐term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neuropathy

Norio Hotta, Ryuzo Kawamori, Masakatsu Fukuda, +1

Diabetic Medicine

Abnormal glutathione metabolism and increased cytotoxicity caused by H2O2 in human umbilical vein endothelial cells cultured in high glucose medium

Atsunori Kashiwagi, T. Asahina, M. Ikebuchi, +5

Diabetologia

Abnormal Glutathione MetabolismBiochemistryLipid PeroxidationDiabetesPhysiology +9

Effect of a new aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) on peripheral nerve disorders in streptozotocin-diabetic rats

Ryuichi Kikkawa, Ikuo Hatanaka, H. Yasuda, +5

Diabetologia

BiochemistryMedicineDiabetesPhysiologyStreptozotocin-diabetic Rats +7

Translocation of protein kinase C ? and ? in rat glomerular mesangial cells cultured under high glucose conditions

Ryuichi Kikkawa, Masakazu Haneda, T. Uzu, +3

Diabetologia

Molecular PhysiologySignal TransductionProtein Kinase CHigh Glucose ConditionsPhysiology +8

Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes

Y. Harano, Atsunori Kashiwagi, Hideto Kojima, +3

FEBS Letters

Mr 69000Cellular PhysiologyCarnitine PalmitoyltransferaseIsolated Rat HepatocytesReceptor Tyrosine Kinase +16

Clinical investigation of epalrestat, an aldose reductase inhibitor, on diabetic neuropathy in Japan: Multicenter study

Nigishi Hotta, Nobuo Sakamoto, Y. Shigeta, +2

Journal of Diabetes and its Complications

Metabolic SyndromeHypertensionUrologyMedicineDiabetes +7

Direct automated assay method for serum or urine levels of ketone bodies

Y. Harano, Masatsugu Ohtsuki, Maiorino Maria Ida, +7

Clinica Chimica Acta

Urine LevelsUrologyEngineeringMedicineBioanalysis +10

Effects of an aldose reductase inhibitor, epalrestat, on diabetic neuropathy. Clinical benefit and indication for the drug assessed from the results of a placebo-controlled double-blind study

Y. Goto, Norio Hotta, Y. Shigeta, +2

Biomedicine & Pharmacotherapy

Diabetes ManagementMedicineDiabetesDiabetic NeuropathyPharmacotherapy +5