Concepedia

An efficient synthesis of 2,3,4‐trisubstituted quinolines through alkynylation‐cyclization at ambient temperature

Dipti R. Patil, Sonali M. Salunkhe, M. B. Deshmukh, Prashant V. Anbhule

Journal of Heterocyclic Chemistry · 2011 · 13 citations · 33 references

DOI

Concepts

Abstract

Abstract A series of 2,3,4‐trisubstituted quinoline derivatives have been synthesized by reactions between 2‐aminoaryl ketones and dialkyl acetylenedicarboxylate. The synthetic pathway allows for the direct construction of said quinoline derivatives in pyridine/ethanol at ambient temperature through a zwitterion intermediate. J. Heterocyclic Chem., (2011)

References

33

New Conjugated Polymers with Donor−Acceptor Architectures:  Synthesis and Photophysics of Carbazole−Quinoline and Phenothiazine−Quinoline Copolymers and Oligomers Exhibiting Large Intramolecular Charge Transfer

Samson A. Jenekhe, Liangde Lu, Maksudul M. Alam · Macromolecules · 2001 · 772 citations

, , +17

A novel and efficient one step synthesis of 2-amino-5-cyano-6-hydroxy-4-aryl pyrimidines and their anti-bacterial activity

M. B. Deshmukh, S. M. Salunkhe, D. R. Patil et al. · European Journal of Medicinal Chemistry · 2008 · 208 citations

, , +8

Anticancer activity for 4,4′-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007) analogues and Their abilities to interact with lymphoendothelial cell surface markers

Lee Roy Morgan, Branko S. Jursic, Catherine L. Hooper et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 185 citations

, , +12

A Novel Synthesis of 2-Aminopyrroles Using a Three-Component Reaction

Vijay Nair, A. U. Vinod, C. Rajesh · The Journal of Organic Chemistry · 2001 · 179 citations

, , +5

Zn(II)-Mediated Alkynylation−Cyclization of <i>o</i>-Trifluoroacetyl Anilines:  One-Pot Synthesis of 4-Trifluoromethyl-Substituted Quinoline Derivatives

Biao Jiang, Yu‐Gui Si · The Journal of Organic Chemistry · 2002 · 167 citations

, , +7