Further evidence for a synergistic association between APOE ?4 and BCHE -K in confirmed Alzheimer's disease

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Type 4, Genetics, Genetic Epidemiology +18

CHANGES IN BRAIN CHOLINESTERASES IN SENILE DEMENTIA OF ALZHEIMER TYPE

Elaine K. Perry, R. H. Perry, G. Blessed et al. · Neuropathology and Applied Neurobiology · 1978 · 550 citations

Alzheimer Type, Alzheimer's Disease, Aging +15

The use of a genetic map of biallelic markers in linkage studies

Leonid Kruglyak · Nature Genetics · 1997 · 494 citations

Genetic Analysis, Linkage Disequilibrium, Genotype-phenotype Association +11

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene

Deborah A. Nickerson, Scott L. Taylor, Kenneth M. Weiss et al. · Nature Genetics · 1998 · 477 citations

Dna Sequencing, Medicine, Genetics +6

Comparative Alterations of Nicotinic and Muscarinic Binding Sites in Alzheimer's and Parkinson's Diseases

Isabelle Aubert, Dalia M. Araujo, Danielle Cécyre et al. · Journal of Neurochemistry · 1992 · 320 citations