Concepedia

Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: Safety, pharmacokinetics and ammonia control

Brendan Lee, William J. Rhead, George A. Díaz, Bruce F. Scharschmidt, Asad Mian, Oleg A. Shchelochkov, Jean‐Francois Marier, Martin Béliveau, Joseph Mauney, Klara Dickinson

Molecular Genetics and Metabolism · 2010 · 90 citations · 8 references

DOI

Concepts

References

8

Survival after Treatment with Phenylacetate and Benzoate for Urea-Cycle Disorders

Gregory M. Enns, Susan A. Berry, Gerard T. Berry et al. · New England Journal of Medicine · 2007 · 355 citations · Full text

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Urea Cycle Disorders: Diagnosis, Pathophysiology, and Therapy

Saul W. Brusilow, Nancy E. Maestri · Advances in Pediatrics · 1996 · 354 citations

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Diagnosis, symptoms, frequency and mortality of 260 patients with urea cycle disorders from a 21‐year, multicentre study of acute hyperammonaemic episodes

Marshall Summar, Dries Dobbelaere, Saul W. Brusilow et al. · Acta Paediatrica · 2008 · 235 citations · Full text

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Cross-sectional multicenter study of patients with urea cycle disorders in the United States

Mendel Tuchman, Brendan Lee, Uta Lichter‐Konecki et al. · Molecular Genetics and Metabolism · 2008 · 218 citations · Full text

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Phenylacetylglutamine May Replace Urea as a Vehicle for Waste Nitrogen Excretion

Saul W. Brusilow · Pediatric Research · 1991 · 170 citations · Full text

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