Concepedia

Determinants of Decline in Glomerular Filtration Rate in Nonproteinuric Subjects with or without Diabetes and Hypertension

Hiroki Yokoyama, Sakiko Kanno, Suguho Takahashi, Daishiro Yamada, Hiroshi Itoh, Kazumi Saito, Hirohito Sone, Masakazu Haneda

Clinical Journal of the American Society of Nephrology · 2009 · 75 citations · 25 references

DOIFull text

Open access

Abstract

GFR slope is substantially affected by multiple factors at various stages. The degree of chronic hyperglycemia is likely to play a crucial role in elevating GFR and accelerating the decline in patients with type 2 diabetes even from the normoalbuminuric stage.

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