Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

G proteins and dual control of adenylate cyclase

Alfred G. Gilman · Cell · 1984 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +12

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

Martin Rodbell · Nature · 1980 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +16

Ionic currents in single isolated bullfrog atrial cells.

Joseph R. Hume, Wayne R. Giles · The Journal of General Physiology · 1983 · 167 citations · Full text

Natural Sciences, Biophysics, Physiology +17

Reciprocal modulation of agonist and antagonist binding to muscarinic cholinergic receptor by guanine nucleotide.

Ernst Bürgisser, A. De Léan, Robert J. Lefkowitz · Proceedings of the National Academy of Sciences · 1982 · 132 citations · Full text

Medicine, Pharmacology, Physiology +17