Six Novel Missense Mutations in the LDL Receptor-Related Protein 5 (LRP5) Gene in Different Conditions with an Increased Bone Density

LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

Yaoqin Gong, Roger B. Slee, Georges Rawadi et al. · Cell · 2001 · 2.2K citations · Full text

Medicine, Developmental Biology, Endocrinology +10

High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

Lynn M. Boyden, Junhao Mao, Joseph L. Belsky et al. · New England Journal of Medicine · 2002 · 1.6K citations · Full text

Medicine, Molecular Genetics, Oncology +17

A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

Randall D. Little, Colleen Folz, Susan P. Manning et al. · The American Journal of Human Genetics · 2002 · 1.3K citations · Full text

Medicine, Genetics, Molecular Genetics +12

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

Wendy Balemans · Human Molecular Genetics · 2001 · 1.1K citations · Full text

Medicine, Genetics, Molecular Genetics +14

<i>Cbfa1</i>-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

Masaki Kato, Millan S. Patel, Régis Levasseur et al. · The Journal of Cell Biology · 2002 · 1.1K citations · Full text

Medicine, Developmental Biology, Molecular Biology +17