Concepedia

Enantioselective synthesis of bicyclo[2.2.2]octane-1-carboxylates under metal free conditions

Yingzi Li, Jie Wang, Wangbin Sun, Yifan Shan, Bingfeng Sun, Guo‐Qiang Lin, Jian‐Ping Zou

Organic Chemistry Frontiers · 2015 · 10 citations · 67 references

DOI

Concepts

Abstract

A new tandem reaction permits rapid access to bicyclo[2.2.2]octane-1-carboxylates with excellent enantioselectivities under metal free, mild, and operationally simple conditions.

References

67

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, , +9

Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea

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Enantio‐ and Diastereoselective Michael Reaction of 1,3‐Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea.

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Highly Enantioselective Conjugate Addition of Malonate and β-Ketoester to Nitroalkenes:  Asymmetric C−C Bond Formation with New Bifunctional Organic Catalysts Based on Cinchona Alkaloids

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