Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2003 · 37 citations · 0 references
EngineeringMicroscopyVoxel ShapeBiomedical EngineeringMicro-optical ComponentLight MicroscopyBiophysicsRadiologyPhotonicsPhysicsBiophotonicsPhotonic DeviceIntensity DistributionVoxel ShapesOptical ImagingMicrofabricationApplied PhysicsBiomedical ImagingAspect RatioMedicine
Maximization of scan speed and throughput while maintaining resolution is critical for commercialization of two-photon microfabrication technology. We report contrast curves for cationic and free radical two-photon polymerization. An unusual relationship between voxel shape and dose is observed where the voxel ranges from highly asymmetric (aspect ratio of 4:1 or greater) at high dose to nearly spherical low dose (aspect ratio 1:1 or lower). Similar behavior is observed for both types of polymerization systems suggesting that the change is aspect ratio is not a function of the specific type of chemistry. It is found that a simple optical model describing the intensity distribution near the focal point can predict the change in aspect ratio.