Ursolic acid attenuates lipopolysaccharide-induced cognitive deficits in mouse brain through suppressing p38/NF-κB mediated inflammatory pathways

Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes

Taro Kawai, Osamu Takeuchi, Takashi Fujita et al. · The Journal of Immunology · 2001 · 1.1K citations · Full text

Life Sciences, Immunology, Microbiology +16

Phosphorylation of human I kappa B‐alpha on serines 32 and 36 controls I kappa B‐alpha proteolysis and NF‐kappa B activation in response to diverse stimuli.

E. Britta-Mareen Traenckner, Heike L. Pahl, Timothy P. Henkel et al. · The EMBO Journal · 1995 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Broad Expression of Toll-Like Receptors in the Human Central Nervous System

Malika Bsibsi, Rivka Ravid, Djordje Gverić et al. · Journal of Neuropathology & Experimental Neurology · 2002 · 992 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

Mausumee Guha, Nigel Mackman · Journal of Biological Chemistry · 2002 · 789 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

Colm Cunningham, David Wilcockson, Suzanne Campion et al. · Journal of Neuroscience · 2005 · 772 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17