Concepedia

MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4

Wentao Tang, Yunxia Zhu, Jie Gao, Junjiang Fu, C Liu, Yun Liu, Chun Song, Shuguang Zhu, Yumei Leng, G Wang,

British Journal of Cancer · 2013 · 182 citations · 45 references

DOIFull text

Open access

Abstract

Increased expression of miR-29a promoted CRC metastasis by regulating MMP2/E-cad through direct targeting KLF4, which highlights the potential of the miR-29a inhibitor as a novel agent against CRC metastasis.

References

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