The Journal of Gene Medicine · 2001 · 689 citations · 26 references
Branched and linear PEI/DNA complexes differ in their ability to transfect cells. The greater efficiency of linear PEI might be due to an inherent kinetic instability under salt conditions. Understanding how to employ this kinetic instability of linear PEI could help in designing future vectors with greater flexibility and transfection efficiency in vivo.
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Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text
Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations