Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Anne J. Ridley, Alan Hall · Cell · 1992 · 4.5K citations

Mechanobiology, Focal Adhesions, Actin Stress Fibers +14

Genomic analysis of metastasis reveals an essential role for RhoC

Edwin Clark, Todd R. Golub, Eric S. Lander et al. · Nature · 2000 · 1.4K citations

Oncology, Medicine, Genomic Analysis +7

RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

William T. Arthur, Keith Burridge · Molecular Biology of the Cell · 2001 · 440 citations

Dominant Negative P190rhogap, Cell Adhesion, Molecular Biology +18

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

William T. Arthur, Leslie Petch, Keith Burridge · Current Biology · 2000 · 426 citations · Full text

Signal Transduction, G Protein-coupled Receptor, Cell Signaling +8

Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

Frank Echtermeyer, Michael Streit, Sarah A. Wilcox‐Adelman et al. · Journal of Clinical Investigation · 2001 · 425 citations · Full text