1-phenyl-3-pyrazolidone: An inhibitor of cyclo-oxygenase and lipoxygenase pathways in lung and platelets

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Mats Hámberg, Jan Olof Svensson, B Samuelsson · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

Mats Hámberg, Bengt Samuelsson · Proceedings of the National Academy of Sciences · 1974 · 1.4K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

Mats Hámberg, Jan Svensson, Toshio Wakabayashi et al. · Proceedings of the National Academy of Sciences · 1974 · 998 citations · Full text

Medicine, Biochemistry, Biochemical Pharmacology +10

Isolation and properties of intermediates in prostaglandin biosynthesis

D.H. Nugteren, E. Hazelhof · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1973 · 795 citations

Life Sciences, Biochemistry, Molecular Biology +8