Concepedia

Comparison of EGF with VEGF Non-Viral Gene Therapy for Cutaneous Wound Healing of Streptozotocin Diabetic Mice

Junghae Ko, Hae-Jung Jun, Hyesook Chung, Changshin Yoon, Taekyoon Kim, Minjeong Kwon, Soon‐Hee Lee, Soo Jin Jung, Mi-Kyung Kim, Jeong Hyun Park

Diabetes & Metabolism Journal · 2011 · 37 citations · 29 references

DOIFull text

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Abstract

Both non-viral EGF and VEGF gene therapy administrations could improve the speed and quality of skin wound healing. However, the detailed histological characteristics of the healing wounds were different.

References

29

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Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

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, , +16

Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

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, , +9

Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing.

N. Nissen, Peter J. Polverini, Alisa E. Koch et al. · PubMed · 1998 · 839 citations