Identification of the active site residues in the nsP2 proteinase of sindbis virus

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry · 2013 · 47.3K citations · Full text

Life Sciences, Immunology, Toxicology +17

Rapid and efficient site-specific mutagenesis without phenotypic selection.

Thomas A. Kunkel · Proceedings of the National Academy of Sciences · 1985 · 7.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

Mark J. Zoller, Michael J. Smith · DNA · 1984 · 906 citations

Life Sciences, Genetics, Molecular Biology +15

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

Manuel A. Navia, Paula M.D. Fitzgerald, Brian M. McKeever et al. · Nature · 1989 · 893 citations

Life Sciences, Biochemistry, Molecular Biology +16