Denaturational Stress Induces Formation of Zinc-Deficient Monomers of Cu,Zn Superoxide Dismutase: Implications for Pathogenesis in Amyotrophic Lateral Sclerosis

Superoxide Dismutase

Joe M. McCord, Irwin Fridovich · Journal of Biological Chemistry · 1969 · 12.8K citations · Full text

Life Sciences, Biochemistry, Enzymology +11

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

Life Sciences, Genetics, Neuroscience +14

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations

Life Sciences, Genetics, Neuroscience +17

Enzyme structure and mechanism

D. T. Elmore · Endeavour · 1978 · 2.7K citations

Life Sciences, Biochemistry, Molecular Biology +13

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

Andrew G. Reaume, Jeffrey L. Elliott, Eric K. Hoffman et al. · Nature Genetics · 1996 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17