Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways

Autophagy: cellular and molecular mechanisms

D.R. Glick, Sandra Barth, Kay F. Macleod · The Journal of Pathology · 2010 · 3.8K citations · Full text

Life Sciences, Cell Biology, Pathology +13

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

Abhishek D. Garg, Aleksandra M. Dudek, Gabriela B. Ferreira et al. · Autophagy · 2013 · 298 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS–p38–p53 pathway

Bo Liu, Yan Cheng, Bo Zhang et al. · Cancer Letters · 2008 · 213 citations

Life Sciences, Cell Biology, Oncology +14

A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

A D Kim, Kyoung Ah Kang, H. S. Kim et al. · Cell Death and Disease · 2013 · 155 citations · Full text

Life Sciences, Oncology, Pharmacology +17

FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy

Ning Zhang, Yanfei Qi, Carol Wadham et al. · Autophagy · 2010 · 124 citations · Full text

Medicine, Oncology, Pharmacology +15