Stoffwechselprodukte von Mikroorganismen 198. Mitteilung Die Eurekansäure, ein Abbauprodukt von Flambamycin und Avilamycin: Konfigurationsbestimmung durch Röntgenstrukturanalyse und Abbau

Abstract

Eurekanic Acid, a Degradation Product of Flambamycin and Avilamycin: Determination of the Configuration by X‐Ray Structural Analysis and Degradation The relative configuration of methyl O ‐acetyleurekanate (6) , obtained by mild methanolysis of avilamycin A (2) and subsequent acetylation, was determined by an X‐ray structural investigation. Methyl dihydroeurekanate (7) , similarly obtained from avilamycin C (3) and from reduced avilamycin A methyl ether, was degraded to L‐threonolactone (14) which allowed to determine the chirality of eurekanic acid (4).