The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance to the nematodes Nippostrongylus brasiliensis and Heligmosomoides bakeri

Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells

Mark H. Kaplan, Ulrike Schindler, Stephen T. Smiley et al. · Immunity · 1996 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

Paul S. Foster, Simon P. Hogan, Alistair J. Ramsay et al. · The Journal of Experimental Medicine · 1996 · 1.4K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.

Peter J. Jose, D A Griffiths-Johnson, Paul Collins et al. · The Journal of Experimental Medicine · 1994 · 819 citations · Full text

Life Sciences, Immunology, Pathobiology +14

Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

Padraic G. Fallon, Sarah J. Ballantyne, Niamh E. Mangan et al. · The Journal of Experimental Medicine · 2006 · 725 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.

Paul Ponath, Suofu Qin, D J Ringler et al. · Journal of Clinical Investigation · 1996 · 710 citations · Full text

Life Sciences, Immunology, Molecular Biology +14