Concepedia

Synthesis of a new series of N4-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII

Jarosław Sławiński, Zdzisław Brzozowski, Beata Żołnowska, Krzysztof Szafrański, Aneta Pogorzelska, Daniela Vullo, Claudiu T. Supuran

European Journal of Medicinal Chemistry · 2014 · 23 citations · 22 references

DOI

Concepts

References

22

The Carbon Dioxide Hydration Activity of Carbonic Anhydrase

Raja G. Khalifah · Journal of Biological Chemistry · 1971 · 1.9K citations · Full text

, , +15

Carbonic anhydrase inhibitors

Claudiu T. Supuran, Andrea Scozzafava, Angela Casini · Medicinal Research Reviews · 2002 · 1.4K citations

, , +12

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

Yuanmei Lou, Paul C. McDonald, Arusha Oloumi et al. · Cancer Research · 2011 · 756 citations

, , +17

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

Johanna Chiche, Karine Ilc, Julie Laferrière et al. · Cancer Research · 2008 · 746 citations

, , +17

Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents?

Claudiu T. Supuran, Fabrizio Briganti, Silvia Tilli et al. · Bioorganic & Medicinal Chemistry · 2001 · 275 citations

, , +12