Mouse Small eye results from mutations in a paired-like homeobox-containing gene

Robert E. Hill, Jack Favor, Brigid L.M. Hogan, +7

Nature

Knockout MouseOcular DiseaseDevelopmental BiologyOphthalmologyExperimental Ophthalmology +6

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

Luc St‐Onge, Beatriz Sosa‐Pineda, Kamal Chowdhury, +2

Nature

Cell PhysiologyMolecular PhysiologyDevelopmental BiologyPancreatic CancerCell Signaling +7

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells

Lori Sussel, Julie Kalamaras, Dennis J. Hartigan-O’Connor, +4

Development

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

Maike Sander, Annette Neubüser, Julie Kalamaras, +3

Genes & Development

GeneticsIslet DevelopmentMolecular GeneticsGlucagon ProductionInsulin Signaling +15

Association Between X-Linked Mixed Deafness and Mutations in the POU Domain Gene <i>POU3F4</i>

Yvette J.M. de Kok, Silvère M. van der Maarel, Maria Bitner‐Glindzicz, +6

Science

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.

Jan Jensen, R. Scott Heller, T Funder-Nielsen, +5

Diabetes

Bhlh CascadePremature DifferentiationCell CycleCell SpecializationCellular Physiology +16

Influence of PAX6 Gene Dosage on Development: Overexpression Causes Severe Eye Abnormalities

Andreas Schedl, Allyson Ross, Muriel Lee, +4

Cell

Ocular DiseaseDevelopmental BiologyOphthalmologyGenetic DisorderGenetics +6

The oncogenic potential of Pax genes.

Catharina C. Maulbecker

The EMBO Journal

Pax GenesOncogenic AgentGeneticsGene CharacterizationMolecular Genetics +3

Targeted Mutagenesis of the POU-Domain Gene<i>Brn4/Pou3f4</i>Causes Developmental Defects in the Inner Ear

Deborah Phippard, Lihui Lü, Daniel Lee, +2

Journal of Neuroscience

GeneticsMolecular GeneticsMutant AnimalsBone Morphogenic ProteinBehavioral Anomalies +18

Tissue-specific deletion of <i>Foxa2</i> in pancreatic β cells results in hyperinsulinemic hypoglycemia

Newman J. Sund, Marko Z. Vatamaniuk, Melissa Casey, +5

Genes & Development