New Trial for Endoscopical Observation of Esophagus by Dye Scattering Method

Abstract

Direct dye scattering method, advocated by Schiller in 1933 in order to diagnose the early stage of cervical cancer of the uterus, was adapted to the esophagus epithelium. Five per cent of Lugol's solution was used for this study. From this study on 124 cases of esophagoscopy, normal esophageal epithelium was stained brown and “silk-crape” like surface appearances could be clearly observed on its surface endoscopically, but gastric mucosa was unstained by this method. Inflammatory epithelium and cancerous lesion of the esophagus were also unstained, contrarily whitish granule and leucoplakia were remarkably stained dark brown. This method was useful for differential diagnosis of various esophageal diseases, esophagitis, esophageal cancer, submucosal tumor of esophagus and hiatus hernia. Furthermore, even though the slight changes of mucosal function of the esophagus could be known.