Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

Koichi S. Kobayashi, Mathias Chamaillard, Yasunori Ogura et al. · Science · 2005 · 1.7K citations

Nod2 Protein, Innate Immune System, Immune Regulation +19

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

Naohiro Inohara, Yasunori Ogura, Ana Fontalba et al. · Journal of Biological Chemistry · 2003 · 1.7K citations · Full text

Inflammation, Molecular Immunology, Antimicrobial Drug Discovery +15

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

Mike Rothe, Ming-Gui Pan, William J. Henzel et al. · Cell · 1995 · 1.3K citations · Full text

Inflammation, Tnfr2-traf Signaling, Signal Transduction +11

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

Mathieu J.M. Bertrand, Snezana Milutinovic, Kathleen M. Dickson et al. · Molecular Cell · 2008 · 1.1K citations

Tumor Biology, Cell Regulation, Medicine +8

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

Koichi S. Kobayashi, Naohiro Inohara, Lorraine D. Hernandez et al. · Nature · 2002 · 893 citations · Full text

Inflammation, Signal Transduction, Allergy +13