Investigation on the oxidative N-demethylation of aryl triazenes In vitro

BIOCHEMICAL AND PHARMACOLOGICAL CHANGES IN THE RAT FOLLOWING CHRONIC ADMINISTRATION OF MORPHINE, NALORPHINE AND NORMORPHINE

Joseph Cochin, Julius Axelrod · Journal of Pharmacology and Experimental Therapeutics · 1959 · 747 citations

Medicine, Pharmacology, Biochemical Pharmacology +16

Mechanism of carcinogenesis with 1-Aryl-3,3-dialkyltriazenes. Enzymatic dealkylation by rat liver microsomal fraction in vitro

R. Preußmann, A. von Hodenberg, H Hengy · Biochemical Pharmacology · 1969 · 110 citations

Medicine, Oncology, Pharmacology +13

N-demethylation the antineoplastic agent4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide by rats and man.

Joseph L. Skibba, Diane D. Beal, Guillermo Ramírez et al. · PubMed · 1970 · 100 citations

Medicine, Pharmacokinetics, Pharmacology +9

Studies on the mechanism of action of the tumour inhibitory triazenes

R.C.S. Audette, T.A. Connors, H. George Mandel et al. · Biochemical Pharmacology · 1973 · 88 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Antitumor activity of triazenoimidazoles

Y. Fulmer Shealy, John A. Montgomery, W R Laster · Biochemical Pharmacology · 1962 · 82 citations

Medicine, Medicinal Chemistry, Pharmacology +9