Archives of Surgery · 1987 · 68 citations · 9 references
MedicineNeurosurgerySurgeryCerebrovascular NeurosurgeryCerebrovascular SurgeryVascular SurgeryCarotid Artery SurgeryCarotid EndarterectomyCerebrovascular DiseaseIntracerebral HemorrhageStrokeThrombosisAntiplatelet DrugsCerebral Arterial StenosisCerebral VesselsExtracranial Arterial InvolvementPostoperative Hyperperfusion Syndrome
To our knowledge, a particularly lethal complication of carotid endarterectomy, intracerebral hemorrhage, has not been given due consideration in the literature concerning carotid surgery. In the Atlanta area, massive intracranial hemorrhage developed in ten patients following routine carotid endarterectomies performed during a recent ten-year period. All ten of the patients in this series died despite a variety of therapeutic interventions. Risk factors may include the following: extreme arterial stenosis with resultant postoperative hyperperfusion, involvement of multiple extracranial cerebral vessels, postoperative systemic hypertension, and administration of anticoagulant or antiplatelet medications. Unfortunately, identification of the subset of patients potentially at risk for this complication is difficult, and, to date, therapy has been generally ineffective.
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Normal Perfusion Pressure Breakthrough Theory
Robert F. Spetzler, Charles B. Wilson, Phillip B. Weinstein et al. · Neurosurgery · 1978 · 778 citations
Thoralf M. Sundt, F. W. Sharbrough, D. G. Piepgras et al. · Survey of Anesthesiology · 1982 · 723 citations
Cerebral Hemorrhage in Carotid Artery Surgery
M E Bruetman, William S. Fields, E. Stanley Crawford et al. · Archives of Neurology · 1963 · 163 citations
Medicine, Neurosurgery, Surgery +9