Concepedia

Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors

Izumi Yawata, Hideyuki Takeuchi, Yukiko Doi, Jianfeng Liang, Tetsuya Mizuno, Akio Suzumura

Life Sciences · 2008 · 108 citations · 15 references

DOI

Concepts

References

15

Glutamate neurotoxicity and diseases of the nervous system

Dennis W. Choi · Neuron · 1988 · 8K citations

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Glutamate excitotoxicity in a model of multiple sclerosis

David Pitt, Peter Werner, Cedric S. Raine · Nature Medicine · 2000 · 849 citations

, , +14

Tumor Necrosis Factor-α Induces Neurotoxicity via Glutamate Release from Hemichannels of Activated Microglia in an Autocrine Manner

Hideyuki Takeuchi, Shijie Jin, Jinyan Wang et al. · Journal of Biological Chemistry · 2006 · 741 citations · Full text

, , +17

Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage

Peter Werner, David Pitt, Cedric S. Raine · Annals of Neurology · 2001 · 502 citations

, , +17

Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate

Daniela Piani, Karl Frei, Michel Cuénod et al. · Neuroscience Letters · 1991 · 416 citations

, , +14