Shaping Amorphous Calcium Carbonate Films into 2D Model Substrates for Bone Cell Culture

Abstract

Boning up on patterning: Patterned calcium carbonate films with dimensions of 200–400 μm were obtained using the photolithographic properties of a polysilane-based ABA block copolymer, PHEMA-PMPS-PHEMA. These patterns may serve as a 2D model system for CaCO3 biomaterials in which both the CaCO3 resorption by osteoclasts and the calcium phosphate deposition by osteoblasts can be monitored using optical microscopy. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502602_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.