Concepedia

Structure-activity relationships of taxol®: synthesis and biological evaluation of C2 taxol analogs

Shuhui Chen, Vittorio Farina, Jianmei Wei, Craig Fairchild, Stephen W. Mamber, John F. Kadow, Dolatrai M. Vyas, Terrence W. Doyle

Bioorganic & Medicinal Chemistry Letters · 1994 · 42 citations · 16 references

DOI

Concepts

References

16

Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

M. C. Wani, Harold L. Taylor, Monroe E. Wall et al. · Journal of the American Chemical Society · 1971 · 4.1K citations

, , +10

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

, , +9

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull et al. · PubMed · 1988 · 2.4K citations

, , +9

Taxol stabilizes microtubules in mouse fibroblast cells.

Peter B. Schiff, S. B. Horwitz · Proceedings of the National Academy of Sciences · 1980 · 2K citations · Full text

, , +17

Taxol: A Unique Antineoplastic Agent with Significant Activity in Advanced Ovarian Epithelial Neoplasms

William P. McGuire · Annals of Internal Medicine · 1989 · 1.1K citations

, , +16