microRNAs Derived from Circulating Exosomes as Noninvasive Biomarkers for Screening and Diagnosing Lung Cancer

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.6K citations

Novel Mechanism, Systems Biology, Natural Sciences +10

Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening

New England Journal of Medicine · 2011 · 10.7K citations · Full text

Circulating microRNAs as stable blood-based markers for cancer detection

Patrick S. Mitchell, Rachael K. Parkin, Evan M. Kroh et al. · Proceedings of the National Academy of Sciences · 2008 · 7.9K citations · Full text

Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

Claus L. Andersen, Jens Ledet Jensen, Torben F. Ørntoft · Cancer Research · 2004 · 7.1K citations

Engineering, Genetics, Transcriptomics Technology +18

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Xi Chen, Yi Ba, Lijia Ma et al. · Cell Research · 2008 · 4.5K citations · Full text

Medicine, Biomarker Target, Immunology +11