Concepedia

Four Core Genotypes mouse model: localization of the Sry transgene and bioassay for testicular hormone levels

Yuichiro Itoh, Ryan Mackie, Kathy Kampf, Shelly Domadia, Judith Brown, Rachel J. O’Neill, Arthur P. Arnold

BMC Research Notes · 2015 · 119 citations · 70 references

DOIFull text

Open access

Abstract

The Sry transgene in FCG mice is present in multiple copies at one locus on chromosome 3, which does not interrupt known genes. XX and XY mice with the same type of gonad do not show evidence of different androgen levels prenatally.

References

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